Biochemistry


major-biochemistry

Interdisciplinarity is the hallmark of the biological sciences in the 21st century. In addition to a foundation in chemistry and biology, the biochemistry major provides students with an understanding of the central elements of biochemistry and molecular biology. The biochemistry program curriculum is designed to prepare the student for graduate school, medical school, or other professional programs of study. In addition, graduates should be highly competitive in the chemical, pharmaceutical, and biotechnology marketplace.

Modern interdisciplinary challenges in the biological and chemical sciences require that the student be trained in a broad background of chemistry, biophysics, genetics and molecular biology. The Biochemistry major at AMU aims to provide a rigorous and modern introduction to the chemical and biochemical sciences in an environment that incorporates classroom teaching, class-associated lab experiences, an introduction to the scientific literature and an emphasis on independent research. Together, these strategies and opportunities foster the development of independent thinking and complex problem solving skills, along with the technical proficiency characteristic of the effective scientist in the biochemical sciences.

Explore the Biochemistry Program

In addition to the core curriculum, biochemistry majors take the following courses

  • BIOL 211 Biology I with Lab
  • BIOL 303 Genetics with Lab
  • BIOL 305 Molecular Biology with Lab
  • BCHM 305 Biochemistry I with Lab
  • BCHM 306 Biochemistry II with Lab
  • CHEM 125 General Chemistry I with Lab
  • CHEM 126 General Chemistry II with Lab
  • CHEM 221 Organic Chemistry I with Lab
  • CHEM 222 Organic Chemistry II with Lab
  • PHYS 221 University Physics I: Mechanics with Lab
  • PHYS 222 University Physics II: Materials with Lab

Elective Options (Eight credits are required)

  • BICM 415 Advanced Topics in Biochemistry (2 credits)
    • Possible Topics Include:
      • Transcription Control of Gene Expression
      • Biochemistry of Cancer
      • Organic Mechanisms of Drug Action
      • Advanced Structural Biology
      • Biochemistry of Viral Action
      • Advanced Biochemistry Techniques (Lab)
      • Principles of Pharmacology and Pharmacokinetics
      • Enzyme Kinetics and Mechanism
      • Protein Trafficking
      • Natural Products Biochemistry
      • Bio-organic Chemistry
  • BICM 497 Directed Research (Variable credit)

See the Academic Catalog for course descriptions

BIOLOGY COURSES

BIOL 211 Biology I – Cellular and Molecular Biology – An introduction to the study of living systems illustrated by examples drawn from cell biology, biochemistry, genetics, microbiology, neurology and developmental biology. (with lab) (4 cr.)

BIOL 212
Biology II – Organismal and Population Biology – Introduction to the study of organisms emphasizing morphology and physiology, behavior, ecology, and evolution of whole organisms and populations. (with lab) (4 cr.)

BIOL 303 Genetics – Study of the principles of heredity in animals and plants, including the contemporary understanding of genes and gene mechanisms. Laboratory exercises will be used to elucidate genetic principles. (with lab) Prerequisites: BIOL 211, BIOL 212 (4 cr.)

BIOL 305 Molecular Biology – Designed to explore the biology and molecular regulation of gene expression and other cell functions. Other topics include the nature, control, recombination and rearrangement of genes, gene manipulation, and recombinant DNA techniques.(with lab) Prerequisites: BIOL 211, BIOL 212 Recommended: CHEM 211, 212 (4 cr.)

CHEMISTRY COURSES

CHEM 125 General Chemistry I – A study of the basic principles of chemistry, with an emphasis on the laws of chemical combination, descriptive inorganic chemistry, thermochemistry, the gas, liquid, and solid states of matter, the periodic law, atomic structure and chemical bonding, and the nature of intermolecular forces. (with lab) (4 cr.) Prerequisite: MATH 150 or higher

CHEM 126 General Chemistry II – A continuation of General Chemistry I with emphasis on kinetics, chemical equilibria involving gases, weak acids and bases, and slightly soluble solids, free energy changes, electrochemistry, transition metal chemistry. (with lab) (4 cr.) Prerequisite: CHEM 125

CHEM 221 Organic Chemistry I – A detailed study of organic compounds, their synthesis and reactions. An introduction to modern methods of analysis and identification is included. (with lab) (4 cr.) Prerequisite: CHEM 125, CHEM 126

CHEM 222 Organic Chemistry II – A continuation of Organic Chemistry I (with lab) (4 cr.) Prerequisites: CHEM 125, CHEM 126, CHEM 221

BIOCHEMISTRY COURSES

BICM 305 Biochemistry I – A study of proteins, enzymes, carbohydrates, metabolism, signaling pathways, transcription, translation, replication, lipids and membranes with an emphasis on the relationship of structure and function. (4 cr.) Prerequisites: BIOL 211, 212, CHEM 125, 126, 221, 222; PHYS 211, 212, MATH 151

BICM 306 Biochemistry II (Biophysical Chemistry)– This course discusses the concepts of energy, enthalpy, entropy, free energy, thermodynamics, equilibrium, calorimetry and molecular spectroscopy. There is a focus on the application of physical chemistry concepts and mathematics to biological systems. (4 cr.) Prerequisites: BIOL 211, 212; BICH 405, CHEM 125, 126, 221, 222; PHYS 211, 212, MATH 151

BICM 415 Advanced Topics in Biochemistry – These unique courses consist of 2 credit modules, each consisting of 1/2 semester. This format facilitates the student’s exposure to a broad range of topics in modern biochemistry and allows for flexibility in elective course selection.
Possible topics include:
Transcription Control of Gene Expression
Biochemistry of Cancer
Organic Mechanisms of Drug Action
Advanced Structural Biology
Biochemistry of Viral Action
Advanced Biochemical Techniques (lab)
Principles of Pharmacology and Pharmacokinetics
Enzyme Kinetics and Mechanism
Protein Trafficking
Natural Products Biochemistry
Bio-organic Chemistry

BICM 497 Directed Research – Students will be instructed in laboratory and/or library research on a project currently being studied by one or more faculty members. Prerequisite: Faculty approval. (4 cr.)

PHYSICS COURSES

PHYS 221 University Physics I (Mechanics) Mechanics is foundational to physics. Topics include: rectilinear and rotational motions of particles and rigid bodies, energy methods, conservation laws, and Newton’s Law of Universal Gravitation. Pre-requisites: MTH 151 (4 Cr.)

PHYS 222 University Physics II (Materials) – Topics include: materials, oscillations, travelling and standing waves, interference and diffraction, geometric optics, and the Laws of Thermodynamics. The primary objectives of this course are for you to refine your understanding of classical mechanics in the particular and important cases of mechanical oscillations and waves, and for you to study and apply the classical Laws of Thermodynamics. This course includes a laboratory component which is intended to present scientific experimentation as a subject in its own right. Pre-requisites: PHY 221 and MTH 250 (4 Cr.)

The following major equipment is available for research and teaching activities.

Spectroscopy

Cary Eclipse fluorescence spectrophotometer with 96-well plate reader accessory

Cary 50 UV-Vis spectrophotometer with stopped-flow module accessory

Perkin Elmer RX-I Infrared spectrophotometer

Anasazi FT-NMR spectrometer

Proton and carbon probes

GE Storm Fluorescent Gel Imager and Phosphorimager

Beckman LS 6000SC Liquid Scintillation Counter

Molecular Biology

Syngene GeneFlash and GeneGnome gel documentation stations

UVP Ultraviolet Crosslinker and blot hybridization incubator

New Brunswick Inova and G25 Incubator/shakers

PCR thermocycler (several)

Revco ultra-cold freezer

Motic high-resolution dissecting scopes

VanGuard 1400FL Series fluorescent microscope with high resolution camera

Savant DNA Speedvac

Plant grow carts

Centrifugation

Sorvall RC5C PLUS superspeed refrigerated centrifuge

Beckman L8-80M ultracentrifuge

Chromatography

Varian CP-3800 capillary gas chromatograph

HP-Agilent GC-Mass Spectrometer ***NEW 9/09***

BioRad Biologic chromatography system

Computer Resources

Macintosh computer lab with G5 server

Wavefunction Spartan 06 software for molecular mechanics and quantum chemical modeling

Chemical Abstracts SciFinder Scholar Database access with structure search module

Building Facilities

Dark room

Cold room

Media prep room

Amsco Renaissance Series autoclave

Fully equipped research-dedicated labs for biological and chemical research

Tony Barbosa, Ph.D.

Chair of the Chemistry and Physics Department, Assistant Professor of Chemistry
Education: B.S., Chemistry, Providence College; M.S., Organic Chemistry, University of Rochester; Ph.D., Organic Chemistry, University of Rochester
Office: Henkels 3050
Phone: (239) 280-1584

James Vranish, Ph.D.

Assistant Professor of Chemistry
Education: B.S., Biochemistry; Ph.D., Biochemistry & Biophysics, Texas A&M; University of Notre Dame
Office: Henkel’s 3053
Phone: (239) 280-1607

In the last couple years, we have placed our Biochemistry majors in several summer research REU/internship programs at:

  • Harvard/MIT
  • Texas A&M
  • Syracuse University
  • Marian University College of Osteopathic Medicine
  • Pope Paul VI Institute for the Study of Human Reproduction
  • University of South Alabama
  • Eli Lilly Pharmaceuticals

Charlotte Kunkler, 2016 graduate in Biochemistry, is attending the University of Notre Dame pursuing a Ph.D. in Biochemistry

Lexi Hammerquist, 2016 graduate in Biochemistry and AMU Valedictorian, is pursuing a medical degree at Creighton University Medical School

Sarah Downes, 2016 graduate in Biochemistry, is in dental school at the University of Kentucky.

John Robert Griswold, 2015 graduate in Biochemistry and Physics, is in graduate school at the University of South Alabama, Department of Chemical and Biomolecular Engineering

Dominic Buckley, 2015 graduate in Biochemistry, is pursuing a Ph.D. in Biochemistry from the University of Missouri – Kansas City

Megan Rivera, 2015 graduate in Biochemistry, is pursuing a medical degree at Florida State University College of Medicine

Trevor Sasserath, 2015 graduate in Biochemistry, is a Research Associate at the University of Central Florida NanoScience Technology Center and acts as a Cell Biologist at Hesperos

The following students graduated before the introduction of the Biochemistry major but participated in extensive research in the Biochemistry labs:

Joseph Embry, veterinary medicine at Texas A&M
David Hallenbeck, dental school at University of Buffalo
Levi Embry, veterinary medicine at Oklahoma State University
Duy Nguyen, medical school at St. George’s University School of Medicine
Phillip Buckley, Graduate of the University of Kansas School of Dentistry and recipient of the Army Dental Health Scholarship
Dr. Andrew Mullally, Graduate of the Michigan State School of Human Medicine (Michigan State University)
Dan Ade, Indiana University School of Dentistry
Anthony Jay, granted Ph.D. in Biochemistry from Boston University

Do you still have questions about the Biochemistry program at Ave Maria University?

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